Effect of Rewarming Rate During Cardiopulmonary Bypass on Clinical Prognosis of Infants Undergoing Cardiac Surgery

Air Force Military Medical University of People's Liberation Army

Status and phase: Unknown; Phase 2

Conditions: Rewarming Rate; Cardiac Surgery; Cardiopulmonary Bypass

Treatments: Other: Slow rewarming strategy; Other: Fast rewarming strategy

Study type: Interventional

Funder types: Other

Identifiers

NCT01398709

Guch-011

Details and patient eligibility

About

The purpose of this study is to investigate the relationship between rewarming rate during cardiopulmonary bypass and clinical prognosis in infants undergoing cardiac surgery.

Full description

There have been many studies indicating that rewarming management plays an important role in cardiac surgery. The purpose of this study is to investigate the relationship between rewarming rate during cardiopulmonary bypass and clinical prognosis in patients undergoing cardiac surgery. Infants undergoing cardiac surgery with cardiopulmonary bypass are randomly assigned to either a slow rewarming strategy (0.24 degrees C/min) or a fast rewarming strategy (0.5 degrees C/min).

Enrollment: 100 estimated patients

Sex: All

Ages: Under 3 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Infants who had underwent cardiac surgery with cardiopulmonary bypass

Exclusion criteria

• Preoperative liver or kidney disease or dysfunction
• Preoperative coagulation disorder
• Palliative operation or a second operation
• Above 3 years

Trial design

100 participants in 2 patient groups

Slow rewarming strategy

Active Comparator group

Description:

Slow rewarming strategy (0.24 degrees C/min)

Treatment:

Other: Slow rewarming strategy

Fast rewarming strategy

Active Comparator group

Description:

Fast rewarming strategy (0.5 degrees C/min)

Treatment:

Other: Fast rewarming strategy