Effect of Saccharomyces Boulardii on Indirect Hyperbilirubinemia and Phototherapy Duration in Very Low Birth Weight Infants

Zekai Tahir Burak Women's Health Research and Education Hospital

Status and phase: Unknown; Phase 4

Conditions: Indirect Hyperbilirubinemia

Treatments: Dietary Supplement: Reflor; Other: serum physiologic

Study type: Interventional

Funder types: Other

Identifiers

NCT01411761

demirel9800

Details and patient eligibility

About

Indirect hyperbilirubinemia is frequently observed in premature infants.Probiotics are favorable microorganisms that regulate the flora of the gastrointestinal system. In this study we aimed to compare the effect of S. boulardii on severity of hyperbilirubinemia and duration of phototherapy on very low birth weight infants.

Enrollment: 80 estimated patients

Sex: All

Ages: 1 to 15 days old

Volunteers: No Healthy Volunteers

Inclusion criteria

• very low birth weight infants

Exclusion criteria

• chromosomal anomalies

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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80 participants in 2 patient groups, including a placebo group

Saccharomyces boulardii

Experimental group

Description:

study group

Treatment:

Dietary Supplement: Reflor

placebo

Placebo Comparator group

Description:

serum physiologic

Treatment:

Other: serum physiologic