Effect of Saline Lubrication on Post-intubation Complications

Seoul National University

Status: Completed

Conditions: Postoperative Sore Throat

Treatments: Procedure: Dry group; Procedure: Saline group

Study type: Interventional

Funder types: Other

Identifiers

NCT02492646

JHSeo_Saline

Details and patient eligibility

About

The purpose of this study is to evaluate the influence of none-lubricated dry tube on the incidence of Postoperative Sore Throat (POST) after general anesthesia with endotracheal intubation.

Enrollment: 300 patients

Sex: All

Ages: 20 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients aged between 20-80 years who were scheduled for surgery under general anesthesia requiring orotracheal intubation

Exclusion criteria

• history of gastroesophageal reflux disease (GERD)
• congenital or acquired abnormalities of the upper airway such as tumor, polyp, trauma, abscess, inflammation, infection, or foreign bodies
• previous airway surgery; increased risk of aspiration
• coagulation disorders
• previous history of difficult intubation or conditions with expected difficult airway including Mallampati classification ≥ 3 or thyromental distance < 6.5 cm
• Using the other intubation devices beyond the direct laryngoscopy such as lighted stylet or fiberoptic bronchoscopy
• symptoms of sore throat or upper respiratory tract infection
• expected to place nasogastric tube during perioperative period
• requiring nasotracheal intubation

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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300 participants in 2 patient groups

Saline group

Experimental group

Description:

In the saline group, disposable endotracheal tube was immersed in the 1 liter of sterile 0.9% sodium chloride irrigation solution before anesthetic induction.

Treatment:

Procedure: Saline group

Dry group

Experimental group

Description:

In the dry group, endotracheal tube was peeled off from sterile packing just before orotracheal intubation.

Treatment:

Procedure: Dry group