Effect of Sarcopenic Obesity on Weight Loss Outcomes and Quality of Life After Laparoscopic Sleeve Gastrectomy

Fujian Medical University

Status: Completed

Conditions: Sarcopenic Obesity; Body Composition

Treatments: Procedure: Laparoscopic sleeve gastrectomy

Study type: Observational

Funder types: Other

Identifiers

NCT05826210

2023-03

Details and patient eligibility

About

The purpose of this study is to assess the impact of sarcopenic obesity (SO) on weight loss outcomes and improvement of quality of life after laparoscopic sleeve gastrectomy.

Full description

Sarcopenic obesity is a state in which a lack of muscle mass and strength coexists with an increase in fat mass, and it may affect the health outcome of people with obesity after laparoscopic sleeve gastrectomy (LSG).No studies have reported differences in weight loss outcomes between patients with SO and those with non-sarcopenic obesity (NSO) after LSG. Therefore, this study aimed to systematically evaluate the differences in weight loss and quality of life (QOL) evaluation between patients with SO and NSO after LSG and provide high-level evidence-based medical evidence for the impact of SO on weight loss in the obese population and refinement of follow-up strategies.

Enrollment: 245 patients

Sex: All

Ages: 16 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Obese patients who met the indications for LSG and were followed up regularly as planned after surgery.

Exclusion criteria

1. incomplete critical clinical data;
2. incomplete imaging data;
3. insufficient follow-up data.

Trial design

245 participants in 2 patient groups

Sarcopenic obesity group

Description:

Patients who underwent LSG with FM/FFM\>0.80 calculated from the cross-sectional CT image of L3 vertebra.

Treatment:

Procedure: Laparoscopic sleeve gastrectomy

Non-sarcopenic obesity group

Description:

Patients who underwent LSG with FM/FFM\<0.80 calculated from the cross-sectional CT image of L3 vertebra.

Treatment:

Procedure: Laparoscopic sleeve gastrectomy