Effect of scFOS on Increase in Stool Frequency in Constipated People (CONSYST)

Syral

Status

Completed

Conditions

Functional Constipation

Healthy

Treatments

Dietary Supplement: scFOS

Dietary Supplement: Maltodextrin

Study type

Interventional

Funder types

Other

Industry

Identifiers

NCT03707002

PEC14513

Details and patient eligibility

About

The study aims to evaluate the effects of short-chain fructo-oligosaccharides on the frequency and consistency of stools in subjects with functional constipation.

Full description

This randomized, placebo-controlled, double-blind study aims to evaluate the effects of short-chain fructo-oligosaccharides on the frequency and consistency of stools in subjects with functional constipation.

Enrollment

186 patients

Sex

All

Ages

18 to 65 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

functional constipation according to ROME III criteria with 3 or less than 3 stools per week
BMI between 18 and 32kg/m², limits included
Subjects who do not usually eat high-fibre foods
Subjects who do not usually consume foods siad "reduced in sugars" or "light"
Subjects who do not consume regularly pre- and probiotics in the form of dietary supplements

Exclusion criteria

subjects presenting Irritable bowel syndrome
history of chronic GI disorders: crohn disease, ulcerative colitis,....
treatments likely to influence GI sensitivity or motility (laxative, neuroleptics,...)
Antibiotic therapy in progress or in the past 8 weeks
medical history with impact on the study objectives as defined by investigator
known food allergy to one of the compounds of the study product