Effect of Sedatives on Regional Cerebral Oxygen Saturation (2)

Gachon University Gil Medical Center

Status: Withdrawn

Conditions: Cerebral Ischemia-Hypoxia

Treatments: Drug: Midazolam; Drug: Dexmedetomidine

Study type: Interventional

Funder types: Other

Identifiers

NCT02966743

GCIRB2016-293

Details and patient eligibility

About

Compare the changes of regional cerebral oxygen saturation during midazolam or dexmedetomidine sedation for spinal anesthesia in the elderly patients who undergoing femur surgery.

Full description

Compare the changes of regional cerebral oxygen saturation during midazolam or dexmedetomidine administration (target bispectrl index 75-80) for spinal anesthesia in the elderly patients over 65 years who undergoing femur surgery.

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patinets who undergoing femur surgery under spinal anesthesia

Exclusion criteria

• previous cerebrovascular disease, uncontrolled cardiovascular disorder, uncontrolled pulmonary disease

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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0 participants in 2 patient groups

midazolam

Experimental group

Description:

administration of midazolam during spinal anesthesia for target bispectral index 75-80

Treatment:

Drug: Midazolam

dexmedetomidine

Active Comparator group

Description:

administration of dexmedeomidine during spinal anesthesia for target bispectral index 75-80

Treatment:

Drug: Dexmedetomidine