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Effect of Sham Feeding on Postoperative Ileus After Elective Liver Transplantation

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Seoul National University

Status

Completed

Conditions

Postoperative Ileus

Treatments

Other: Control
Other: gum chewing

Study type

Interventional

Funder types

Other

Identifiers

Details and patient eligibility

About

Postoperative ileus is a common after abdominal surgery. Multifactorial etiology such as surgical trauma, bowel manipulation and perioperative opioids contributes to delayed return of normal gut function Chewing gum has recently been used as a form of sham feeding to stimulate acceleration of gut function after abdominal surgery.

The investigators hypothesize that sham feeding with chewing gum will accelerate return of gut function after liver transplantation.

Enrollment

70 patients

Sex

All

Ages

18 to 70 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • elective liver transplantation surgery
  • an ability to chew gum

Exclusion criteria

  • emergency surgery
  • age less than 18 years,
  • inability to provide written informed consent
  • an inability to chew gum
  • hepaticojejunostomy
  • sedated patients
  • reintubated patients
  • Glasgow Coma Scale <13
  • reoperation before gas out
  • previous bowel surgery

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

70 participants in 2 patient groups, including a placebo group

gum chewing
Experimental group
Description:
Gum type was standardized with all subjects receiving sugar-free xylitol gum. The patients in the chewing gum group, gum chewing began the morning of postoperative day 1. Patients chewed gum (two tablets) 3 times daily in the morning, afternoon, and evening for 15 min. The administration of the therapy was implemented by ICU nurses and recorded in the clinical report form file. All gum-chewing patients completed their course of gum chewing until gas out.
Treatment:
Other: gum chewing
Control
Placebo Comparator group
Description:
Routine care during NPO
Treatment:
Other: Control

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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