Effect of Shock Wave In Reducing Chemotherapy- Induced Peripheral Neuropathy In Adult and Pediatric Tumors Patients

South Valley University

Status: Unknown

Conditions: Peripheral Neuropathy

Treatments: Device: The Shock wave Therapy.

Study type: Interventional

Funder types: Other

Identifiers

NCT05111730

P.T.REC/012/002568

Details and patient eligibility

About

This study aimed to assess the efficacy of shock wave in reducing Chemotherapy- Induced Peripheral Neuropathy in adult and pediatric tumors patients.

Full description

Peripheral neuropathy is a serious condition characterized by symmetrical, distal damage to the peripheral nerves that may be caused by several classes of drugs, including chemotherapeutic agents. Chemotherapy-induced peripheral neuropathy (CIPN) is an adverse effect estimated to occur in up to 40% of patients undergoing chemotherapy, with its incidence increasing in patients being treated with multiple agents. Pharmacists play a pivotal role in the prevention and management of CIPN by recommending evidence-based pharmacologic and nonpharmacologic strategies appropriate for the individual patient.Peripheral neuropathy (PN) is a systemic disease characterized by symmetrical, distal damage to the peripheral nerves that negatively impacts patient quality of life (QOL). Prolonged symptoms associated with PN can cause pain, interfere with functional ability (e.g., dressing, driving, house-work), and disrupt emotional health.

Enrollment: 80 estimated patients

Sex: All

Ages: 8 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Their age will ranging from eight to forty years.
• All cases participated in this study will from both sexes.
• All cases receiving chemotherapy as primary treatment, postoperative surgical removal of tumors or with conjunction with radiotherapy
• All cases have polyneuropathy caused by chemotherapy.

Exclusion criteria

• Patient with osteoporosis.
• Patient with DVT.
• Patient have a Pacemaker fitted
• Uncooperative patients

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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80 participants in 2 patient groups

The shockwave Group

Experimental group

Description:

Group (A) study group received medical care and standard chemotherapy and shock wave, three times / week for three successful months.

Treatment:

Device: The Shock wave Therapy.

the traditional treatment group

No Intervention group

Description:

group (B) control group received medical care and standard chemotherapy only.