Effect of Short-term Oxygen During CPET in GUCH

University of Zurich (UZH)

Status: Completed

Conditions: Grown-up Congenital Heart Disease (GUCH)

Treatments: Procedure: Sham room air; Procedure: Oxygen application

Study type: Interventional

Funder types: Other

Identifiers

NCT04076501

KEK-ZH-NR. 2012-0251_4

Details and patient eligibility

About

In a randomized, sham-controlled crossover trial the investigators will test whether supplemental oxygen given during cardiopulmonary exercise testing will improve exercise performance and physiological parameters in patients with grown-up congenital heart disease.

Enrollment: 7 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• GUCH, stable medication for at least 4 weeks.

Exclusion criteria

• instable status, pregnancy, clinically relevant concomitant diseases, inability to follow the study procedures

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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7 participants in 2 patient groups

Supplemental oxygen

Experimental group

Description:

Supplemental oxygen will be applied via a mask during CPET

Treatment:

Procedure: Oxygen application

Sham room air

Sham Comparator group

Description:

Room air will be applied similarly to oxygen

Treatment:

Procedure: Sham room air