Effect of Short-term Portable Air Purifier Use on Occupant Health Indicators

Shanghai Jiao Tong University

Status: Completed

Conditions: Non-smoking, Healthy Adults

Treatments: Device: True-Washout-Sham Air Filtration Intervention; Device: Sham-Washout-True Air Filtration Intervention

Study type: Interventional

Funder types: Other

Identifiers

NCT02736487

2015[38]

Details and patient eligibility

About

The purpose of this research project is to examine whether short-term use of portable air pollution filtration can result in changes in indoor airborne pollutants and impact on cardiovascular and respiratory health outcomes of the inhabitants.

Full description

This study will focus on evaluating the short-term benefits of a common portable air purifier technology in reducing air pollutant exposure and the anticipated concomitant health impacts. High ambient levels of various air pollutants in the Shanghai area serve as a useful model to test the portable air purifier intervention in a realistic setting. As most people using a portable air purifier would only be able to do so in their residences, the investigators have designed our study only to test residential air purifier use. Our hypothesis is that the reduction in pollutant concentrations in indoor air caused by the air purifier will result in measurable reductions in risk factors for cardiovascular and respiratory diseases.

Enrollment: 72 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy, non-smoking adults
• Live in the dormitory building at Shanghai First People's Hospital (South Section).

Exclusion criteria

• Current smokers
• Has any of the following diseases: chronic respiratory, cardiovascular, liver, renal, hematological disease; diabetes mellitus;
• Has any other diseases that may confound or complicate the effects of the intervention
• Pregnant females

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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72 participants in 2 patient groups

Group A: True-Washout-Sham

Active Comparator group

Description:

Subjects in group A receives true air filtration intervention, then at least two weeks of washout period, followed by sham air filtration intervention.

Treatment:

Device: True-Washout-Sham Air Filtration Intervention

Group B: Sham-Washout-True

Active Comparator group

Description:

Subjects in group B receives sham air filtration intervention, then at least two weeks of washout period, followed by true air filtration intervention.

Treatment:

Device: Sham-Washout-True Air Filtration Intervention