Effect of Sleep Apnea on Blood Pressure Control and Outcome Early After Subarachnoid Hemorrhage

University Hospital Bonn (UKB)

Status: Unknown

Conditions: Subarachnoid Hemorrhage; Sleep Apnea

Treatments: Device: Sleep Apnea Screening (Out of Center Polysomnography Device)

Study type: Observational

Funder types: Other

Identifiers

NCT02724215

025/16

Details and patient eligibility

About

In this observational study patients with subarachnoid hemorrhage (SAH) will be screened for sleep apnea (SA) to investigate if SA is associated with impaired blood pressure control and worse clinical outcome early after SAH.

Full description

Patients admitted with non-traumatic SAH will be consented and screened for sleep apnea within 48 hours after hospital admission. Blood pressure and clinical outcome will be monitored throughout ICU treatment and hospital stay, respectively. Diagnosis of sleep apnea will be confirmed on follow-up 3-6 month after SAH by sleep apnea screening (portable cardiorespiratory monitoring and out-of-center polysomnography, respectively).

Enrollment: 200 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Subarachnoid Hemorrhage (Hunt & Hess 1 to 4)
• > 18 years of age
• Ability to consent for study of healthcare proxy able to confirm patient will to participate

Exclusion criteria

• Stoke within 3 month prior to admission
• Intubation prior or within 24 hours after admission
• no healthcare proxy

Trial design

200 participants in 2 patient groups

Patients with Sleep Apnea

Description:

Patients with increased apnea-hypopnea-index (\>5/h)

Treatment:

Device: Sleep Apnea Screening (Out of Center Polysomnography Device)

Patients without Sleep Apnea

Description:

Patients with normal apnea-hypopnea-index (5/h and below)

Treatment:

Device: Sleep Apnea Screening (Out of Center Polysomnography Device)