Effect of Sleep Disorder on the Development of Lung Tumors

Shanghai Jiao Tong University

Status

Not yet enrolling

Conditions

Sleep Disorder, Lung Tumor

Study type

Observational

Funder types

Other

Identifiers

NCT05745506

IIT-2022-0160

Details and patient eligibility

About

The goal of this observational study is to observe the lung tumor development in lung tumor patients with long-term sleep disorder. The main questions it aims to answer are:

will long-term sleep disorder promote the malignancy of lung tumor
if so, how exactly will the microenvironment of lung tumor change Participants will receive PSQI scale and MRI functional brain imaging before surgery, blood and tumor tissue will be collected during the surgery.

Researchers will set non-sleep disorder group as control group to see if lung tumor microenvironment change when long-term sleep disorder exists in lung tumor patiens.

Enrollment

200 estimated patients

Sex

All

Ages

18 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

18-75 years old
elective sublobectomy for primary lung tumor
ASA grade I-II
Informed consent of the patient or family

Exclusion criteria

Combination of serious heart, liver, kidney, central nervous system, blood system, immune system diseases or serious mental illness
Combination of other cancers
untreated active lung infection
patients with preoperative neoadjuvant radiotherapy