Effect of Sleep Extension in Prevention to Sleep Deprivation (SLEEPERF)

Centre Hospitalier Universitaire de Saint Etienne

Status: Enrolling

Conditions: Healthy

Treatments: Other: partial sleep deprivation; Other: Reproductibility; Other: Total sleep deprivation

Study type: Interventional

Funder types: Other

Identifiers

NCT06928168

2024-A02857-40 (Other Identifier)

24CH296

Details and patient eligibility

About

The approach of a competition can be associated to a decrease in sleep duration and quality which can negatively impact athlete's performance and health (injury risk, fall, accident). Ultra-endurance competitions even involve partial and/or total sleep deprivation over one or several nights. Studied investigating this question suggest that endurance performance under sleep deprivation is altered, mainly because of an effect on the rate of perceived exertion (RPE), which regulates effort intensity. One of the methods used by athletes to limit the impact of sleep deprivation in competition is to implement sleep extension in the days prior to a competition. However, few studies have investigated the impact of sleep deprivation et its reproducibility on performance and fatigue during a prolonged running exercise, as well as the efficiency of prior sleep extension. The importance of such a preventive measure might also depend on individual resistance to sleep deprivation, which is variable between persons and could have genetic determinants. This aspect remains under-studied, particularly regarding the impact of sleep deprivation on physical performance. Therefore, this study aims at investigating the effects of sleep deprivation and prior sleep extension on prolonged duration performance.

Enrollment: 69 estimated patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Volunteer who signed the written consent form.
• Man or woman.
• Aged 18-50.
• Physically active and running at least one session of more than one hour per week.
• Haven't participated in any competition in the month before the first visit.
• Not participating in any competition during the study.
• Usual sleep time between 6h-8h per night.

Exclusion criteria

• • Any chronic pathology.
• Working night shift.
• Having sleep disorders: score > 5 at Pittsburg Sleep Quality Index.
• Excessive sleepiness: score >10 at Epworth Sleepiness scale.

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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69 participants in 3 patient groups

REP (reproducibility).

Experimental group

Description:

This group will perform an incremental running test, driven to exhaustion, after a night of total sleep deprivation twice, at least two weeks apart.

Treatment:

Other: Reproductibility

PT (total sleep deprivation).

Experimental group

Description:

This group will perform an incremental running test, conducted until exhaustion, in: * a control condition (usual sleep) * a one-night condition of partial sleep deprivation * a one-night partial sleep deprivation condition with 5 nights of prior extension. The order of conditions will be randomized.

Treatment:

Other: Total sleep deprivation

PP (partial sleep deprivation)

Experimental group

Description:

This group will perform an incremental running test, run to exhaustion, in : * a control condition (usual sleep), * a one-night total sleep deprivation condition * a one-night total sleep deprivation condition with 5 nights of extension beforehand. The order of conditions will be randomized.

Treatment:

Other: partial sleep deprivation