Effect of Sleep Restriction on Decision Making and Inflammation

Institute of Biomedical Research of the Army

Status: Completed

Conditions: Sleep Deprivation

Treatments: Other: Sleep restriction

Study type: Interventional

Funder types: Other

Identifiers

NCT01989741

2012-A00399-34

Details and patient eligibility

About

• hypothesis: sleep restriction in healthy subject trigger alteration of decision making associated with immuno-inflammatory changes
• inclusion criterias: healthy subjects, men, under 35 years, BMI<26, no sleep troubles, intermediate chronotype
• design: 12 subjects, longitudinal study 2 days of baseline, 7 night of sleep restriction (4h sleep/night), recovery (1, 2, 3 and 9 normal sleep nights).
• parameters: decision making tests, reaction time, wakefulness test, biological parameters (cathecholamines, pro-inflammatory cytokines...), heart rate, blood pressure
• control of sleep restriction: continuous polysomnographic survey

Enrollment: 12 patients

Sex: Male

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy men, < 35 yr old, BMI<26, intermediate chronotype

Exclusion criteria

• sleep trouble, acute or chronique disease (cardiological, neurological...), women

Trial design

Primary purpose: Health Services Research

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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12 participants in 1 patient group

sleep restriction

Other group

Description:

Longitudinal study of response to sleep restriction. Comparison between baseline values and sleep restriction values

Treatment:

Other: Sleep restriction