Effect of Smoking Cessation on Tuberculosis Treatment Outcomes

Dow University of Health Sciences

Status: Completed

Conditions: Tuberculosis, Pulmonary

Treatments: Behavioral: Behavioural Change Communication; Drug: Bupropion

Study type: Interventional

Funder types: Other

Identifiers

NCT04848246

IRB-898/DUHS/Approval/2017/136

Details and patient eligibility

About

This study was a Randomized Controlled Trial conducted at Ojha Institute of Chest Diseases, Dow University of Health Sciences, Karachi, among pulmonary tuberculosis patients

Enrollment: 292 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• pulmonary tuberculosis patients of age 18 years or above
• registered under Directly Observed Treatment Short course (DOTS) at Ojha Institute of Chest Diseases
• reported to have smoked 100 plus cigarettes in past and currently smoking cigarettes

Exclusion criteria

• Extra pulmonary tuberculosis
• drug resistant tuberculosis
• pregnancy
• positive history of epilepsy

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

292 participants in 3 patient groups

Bupropion

Experimental group

Treatment:

Drug: Bupropion

Behavioral: Behavioural Change Communication

Behavioural Change Communication

Experimental group

Treatment:

Behavioral: Behavioural Change Communication

Control

No Intervention group