Effect of Specific Diet and Physical Activity on Weight and/or Fat Loss

Slovak Academy of Sciences

Status: Completed

Conditions: Obesity

Treatments: Behavioral: Lifestyle Counseling

Study type: Interventional

Funder types: Other

Identifiers

NCT02325804

FEXE- 11/2014

Details and patient eligibility

About

The main purpose of this study is to assess metabolic effects (decreased amount of body fat content, insulin sensitivity and lipid profile improvement) of weight loss intervention based on specific life style counseling (low calorie "metabolic stairs" diet and circuit-based exercise in a comparison to conventional diet and exercise. The main hypothesis is that more significant beneficial metabolic effects will have specific life style counseling effect than conventional diet and exercise. The main purpose of this study is to assess above mentioned metabolic changes before and after 6-8 weeks of weight loss intervention.

The investigators will also study the following:

1. The impact of life style counseling induced weight and/or fat loss on physical fitness
2. The impact of life style counseling induced weight and/or fat loss on metabolic parameters (e.g. insulin sensitivity, lipid profile, ect.)

Full description

I

Enrollment: 60 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy Volunteers
• BMI≥25 kg/m2

Exclusion criteria

• Thyroid disease
• Chronic diseases(rheumatic,liver, kidney, pulmonary, etc. diseases) have current signs or symptoms of severe, progressive or uncontrolled renal, hepatic, hematologic, gastrointestinal, endocrine, pulmonary, cardiac, neurologic, or cerebral disease, or diabetes;
• chronic infections
• show evidence of malignancy
• be women who are pregnant, nursing
• medical treatment except allergy medicines
• tobacco, alcohol or drug addiction

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

Conventional lifestyle counseling

Active Comparator group

Description:

Randomized, open label study to assess effect of 8 weeks of Conventional lifestyle counseling (low calorie diet and exercise) on body composition, physical fitness, and metabolic parameters

Treatment:

Behavioral: Lifestyle Counseling

Unconventional lifestyle counseling

Active Comparator group

Description:

Randomized, open label study to assess effect of 8 weeks of unconventional lifestyle counseling (low calorie "metabolic stairs" diet and circuit-based exercise) on body composition, physical fitness, and metabolic parameters

Treatment:

Behavioral: Lifestyle Counseling