Effect of Spirulina on Periodontitis

Kafrelsheikh University

Status: Completed

Conditions: Periodontitis

Treatments: Procedure: SRP of all teeth; Drug: spirulina gel

Study type: Interventional

Funder types: Other

Identifiers

NCT06016933

5

Details and patient eligibility

About

The purpose of this study is to assess the clinical and immunological effect of spirulina in treatment of stage II periodontitis.

Full description

In this study, the investigators tested the effect of spirulina gel as adjunctive of scaling and root planing in treatment of stage II, grade B periodontitis in term of probing pocket depth reduction, mean gain in clinical attachment level, and level of interleukin 6.

Enrollment: 40 patients

Sex: All

Ages: 35 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All the patients suffer from stage II, grade B periodonitis with attachment loss 3-4 mm and probing pocket depth ≤ 5mm.

Exclusion criteria

• Any systemic disease that affects the periodontium. ·
• Pregnant, postmenopausal women. ·
• People who take anti-inflammatory drugs, antibiotics, or vitamins within the previous 3 month.
• People who use mouth washes regularly ·
• Participation in other clinical trials.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 2 patient groups, including a placebo group

oral hygiene instructions and SRP of all teeth plus placebo gel.

Placebo Comparator group

Treatment:

Procedure: SRP of all teeth

oral hygiene instructions and SRP of all teeth, followed by insertion of the spirulina gel.

Active Comparator group

Treatment:

Procedure: SRP of all teeth

Drug: spirulina gel