Effect of Statins on Lipid Levels Following the First Acute Coronary Event (MK-0000-204) (REMAINS)

Merck Sharp & Dohme (MSD)

Status: Completed

Conditions: High LDL-C; Dyslipidemias; Hypertriglyceridemia; Hypercholesterolemia; Low HDL-C

Study type: Observational

Funder types: Industry

Identifiers

NCT01245738

CTRI/2013/02/003429 (Registry Identifier)

0000-204

Details and patient eligibility

About

The current study is proposed to investigate the pattern of dyslipidemia and of lipid treatment practices in patients in India experiencing their first acute cardiovascular event and the extent of residual dyslipidemia after 12 weeks of treatment with statins. Dyslipidemia definitions are per the National Cholesterol Education Program - Adult Treatment Panel III (NCEP-ATP III).

Enrollment: 635 patients

Sex: All

Ages: 35+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Currently admitted with a confirmed diagnosis of first acute coronary event (STEMI/NSTEMI/Unstable Angina)
• Access to medical records covering the entire study period, and availability of data required for the study
• Potential to collect blood sample within 24 hours of onset for symptoms
• Considered for initiation/maintenance/modification of statin therapy before discharge from hospital
• Willing to comply with the study requirements

Exclusion criteria

• Participating in a clinical trial or any type of other clinical study involving therapeutic intervention or otherwise failing to consent to interview
• Known inherited disorder of lipoprotein metabolism
• History of hypothyroidism, nephrotic syndrome, chronic alcoholism, Cushing syndrome

Trial design

635 participants in 1 patient group

Participants

Description:

Participants admitted to participating tertiary cardiac care centers who experienced a first coronary event.