Effect of Stellate Ganglion Block on New Atrial Fibrillation After Coronary Artery Bypass Grafting

Yangzhou University

Status

Completed

Conditions

Stellate Ganglion Block

Treatments

Procedure: Stellate nerve block

Study type

Interventional

Funder types

Other

Identifiers

NCT05932485

20230609

Details and patient eligibility

About

Post-operative new-onset atrial fibrillation (POAF) is one of the most common arrhythmias in adults after direct intracardiac surgery with extracorporeal circulation. The incidence of POAF in coronary artery bypass grafting (CABG) is approximately 30%. POAF can lead to an increased risk of complications such as stroke, heart failure, and acute kidney injury, which not only prolongs the patient's hospital stay, but also increases hospital costs and mortality. operation, extracorporeal circulation, and the patient's underlying conditions (such as age, gender, hypertension, and diabetes), which cause sympathetic activation, inflammatory response, and myocardial ischemia in the organism. The stellate ganglion block (SGB) regulates the sympathetic tone of the innervated nerves and thus the autonomic function of the body. SGB can effectively regulate the sympathetic-parasympathetic imbalance. Also, SGB may exert some anti-inflammatory effects. In this study, ultrasound-guided SGB was used in CABG patients to investigate its effect on the occurrence of POAF.

Enrollment

108 patients

Sex

All

Ages

18 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients undergoing first-time and elective coronary artery bypass grafting;
ASA grade II-IV；
The preoperative ECG showed sinus heart rate.

Exclusion criteria

The patient refused to participate in this study;
Surgical procedures include any other type of heart surgery in addition to CABG；
Allergic to known general anesthesia drugs;
Patients with a history of neck surgery or abnormal neck anatomy;
Patients with contraindications to SGB.