ClinicalTrials.Veeva

Menu

Effect of Sulfur Thermal Water on Circulating H2S Levels and Markers of Bone Metabolism in Osteopenic Subjects. (FORST3)

I

Istituto Ortopedico Rizzoli

Status

Completed

Conditions

Osteoporosis
Hydrogen Sulfide

Treatments

Other: inhalatory treatment with sulfureous aerosol

Study type

Interventional

Funder types

Other

Identifiers

Details and patient eligibility

About

The aim of the study is to investigate whether inhalation treatment with high-sulfide waters from some spas (referred to as "thermal waters"), performed for 12 consecutive days, is able to change circulating H2S levels and alter bone metabolism. Identifying a clear correlation between circulating levels of H2S and sulfur water administration, as well as a potential anabolic effect on bone, would set the stage for new studies that could have important clinical implications for promoting health and preventing osteoporosis

Enrollment

50 patients

Sex

Female

Ages

50 to 60 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • post-menopausal women with a diagnosis of osteopenia

Exclusion criteria

  • concurrent muscoloskeletal conditions or chronic pharmacological treatment interfering with bone metabolism

Trial design

Primary purpose

Prevention

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

50 participants in 1 patient group

Bone turnover markers
Experimental group
Description:
Concentrations of bone turnover markers will be assessed before and after treatment. Correlation will be sought for with H2S levels and clinical features of the patients
Treatment:
Other: inhalatory treatment with sulfureous aerosol

Trial contacts and locations

1

Loading...

Central trial contact

Francesco Grassi, Ph.D; Brunella Grigolo, Ph.D

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2024 Veeva Systems