Effect of Supragingival Irrigators Containing Chlorhexidine on Oral Health in Blood Dyscrasia

Mashhad University of Medical Sciences

Status and phase

Completed

Phase 2

Conditions

Thrombocytopenia

Chemotherapy

Blood Dyscrasia Patients

Severe Neutropenia

Treatments

Device: supragingival irrigators containing chlorhexidine

Study type

Interventional

Funder types

Other

Identifiers

NCT01974401

89462

Details and patient eligibility

About

in this study , effectiveness of supragingival irrigators containing chlorhexidine is compared with routine oral health measures in patients with blood dyscrasia whom can not use effective oral health measures(e.g brushing ) due to their systemic condition(e,g,neutropenia ,thrombocytopenia,..)

Full description

Since some patients with hematologic malignancies cannot brush effectively and are at increased risk of bleeding and infection due to severe neutropenia and thrombocytopenia we want to access whether a none invasive method ( water jet systems containing chlorhexidine ) Can help this patients to get better oral health indexes in comparison with routine oral health measures in these type of patients.

Enrollment

20 patients

Sex

All

Ages

12 to 60 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

patients with a blood dyscrasia, severe neutropenia and thrombocytopenia, absence of periodontitis, absence of any oral mucosal lesion in onset of study, patient consent

Exclusion criteria

diabetes mellitus, observation of any side effect (resulted from the device), severe oral mucositis in intervention group(grade 3 and4 WHO), edentulousness, intolerance of device in severely malaise patients, patient death