Effect of TCI188 Probiotic on Oral Health

TCI

Status: Completed

Conditions: Periodontal Diseases

Treatments: Dietary Supplement: Placebo; Dietary Supplement: TCI188 Probiotic

Study type: Interventional

Funder types: Industry

Identifiers

NCT06141083

N202307006

Details and patient eligibility

About

To assess the efficacy of TCI188 (Pediococcus acidilactici) Probiotic on Oral Health

Enrollment: 55 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Male or female over 18 years old
• Participants suffer from severe periodontal disease throughout the mouth with symptoms at third and fourth stages, do not have immediate indications for the extraction of multiple teeth or complex denture stimulation, and have not undergone periodontal planing within one year.

Exclusion criteria

• Participants have had periodontal or antimicrobial treatment within the past 6 months
• Participants are smokers, pregnant or with systemic diseases
• Participants had probiotic supplements or with history of adverse reactions to lactose or fermented dairy products

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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55 participants in 2 patient groups, including a placebo group

Placebo chewable tablets

Placebo Comparator group

Treatment:

Dietary Supplement: Placebo

TCI188 Probiotic chewable tablets

Experimental group

Treatment:

Dietary Supplement: TCI188 Probiotic