Effect of TEAS on the Incidence Rate of SIRS in Patients Undergoing Abdominal Surgery

Air Force Military Medical University of People's Liberation Army

Status: Completed

Conditions: Inflammation; Systemic Inflammatory Response Syndrome

Treatments: Device: Sham TEAS; Device: TEAS

Study type: Interventional

Funder types: Other

Identifiers

NCT02193477

Gjian

Details and patient eligibility

About

The purpose of this study is to access the effect of Transcutaneous Electrical Acupoint Stimulation(TEAS) on the Incidence rate of Systemic Inflammatory Response Syndrome (SIRS) in patients undergoing radical surgery for gastric cancer

Full description

Patients undergoing elective radical surgery for gastric cancer under general anesthesia were randomly assigned to three groups, control group , TEAS group and sham TEAS group.

TEAS group receiving TEAS before general anesthesia induction , 1th day and 2nd day after surgery. TEAS was given through electrodes attached to specific acupoints. The time for TEAS was 30min.

Sham TEAS group receiving sham TEAS before general anesthesia induction , 1th day and 2nd day after surgery. Sham TEAS was given through electrodes attached to non-acupoints. The time for sham TEAS was also 30min.

Control group were given no TEAS. Incidence rates of SIRS in each group were compared .Venous blood samples from all groups(control group , TEAS group and sham TEAS group) were collected before general anesthesia induction,1th day and 3rd day after surgery. Inflammatory cytokines index including interleukin-6,interleukin-10,Tumor Necrosis Factor- alpha(TNF-α),Interferon-γ(IFN-γ),Monocyte Chemotactic Protein 1(MCP-1),IgG,IgM were measured.

Enrollment: 105 patients

Sex: All

Ages: 30 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age>30yrs,<75yrs
• ASA 1-2
• Scheduled for radical surgery for gastric cancer under general anesthesia；
• Informed consented

Exclusion criteria

• Patients with implanted pacemakers
• Patients with severe hypertension or cardiac dysfunction；
• Patients with severe pulmonary disease
• Patients with hemoglobin<90g/L

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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105 participants in 3 patient groups

Control

No Intervention group

Description:

Patients were given no TEAS.

TEAS Treatment

Experimental group

Description:

Patients were given 30min of TEAS before general anesthesia induction, 1th day and 2nd day after surgery.

Treatment:

Device: TEAS

Sham TEAS

Sham Comparator group

Description:

Patients were given 30min of sham TEAS before general anesthesia induction,1th day and 2nd day after surgery.

Treatment:

Device: Sham TEAS