Effect of the Anticholinergic Drug Burden on Postoperative Delirium in Elderly Chinese Patients: A Nested Case-Control Study (ADB and POD)

Hao Li

Status: Completed

Conditions: Delirium - Postoperative

Study type: Observational

Funder types: Other

Identifiers

NCT06931353

ChinaPLAGH-ADB and POD

Details and patient eligibility

About

This study aims to investigate the association between preoperative anticholinergic drugs burden and postoperative delirium in elderly Chinese patients.

Enrollment: 10,536 patients

Sex: All

Ages: 65 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients over 65 years; Undergoing general anesthesia; Inpatients who had surgery between Aprill 1, 2020 and Aprill 1, 2022.

Exclusion criteria

• ASA grade V; preoperative Mini-Mental State Examination (MMSE) score <24;history of neurological disorders (such as cerebrovascular disease or dementia); emergency surgeries; operative duration ≤30 minutes, and cases with >5% missing data.