Effect of the Consumption of Probiotics in the Reduction of Incidence of Carious Lesions in Preschool Children

University of Chile

Status

Completed

Conditions

Caries Prevention

Caries Reduction

Treatments

Dietary Supplement: Experimental: Probiotic enriched milk

Study type

Interventional

Funder types

Other

Identifiers

NCT01648075

Universidad de Chile

Details and patient eligibility

About

Probiotics are microorganisms that when administered in adequate amounts can confer health benefits. In vitro and clinical studies support the idea that lactobacilli have protective effects on oral health. A recent study in which preschoolers consumed milk drinks enriched with Lactobacillus rhamnosus, reported a reduction in caries, as well as additional benefits to children.

The aim of this study is to evaluate the effect of daily consumption of milk beverages enriched with Lactobacillus rhamnosus on the incidence of caries in preschool Chilean children.

Full description

In this randomized controlled trial, preschool children belonging to Integra Foundation will be invited to participate. After obtaining parent´s informed consent, clinical and microbiological testing of saliva at baseline, 6 m, 12m and 18m will be performed. Differences in prevalence and incidence of caries, dmft and microbial diversity between groups will be assessed.

Enrollment

261 patients

Sex

All

Ages

2 to 3 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Healthy children from a general health perspective, with or without cavitated carious lesions at baseline.

Exclusion criteria

Children with systemic disorders who need special care and / or who have intolerance to milk drinks or allergy to any of the components of the experimental and / or placebo beverage.