Effect of the Duration of Preoperative Fasting on Hypotension Induced by General Anesthesia in the Elderly Person (JEÛNE PREOP)

Regional University Hospital Center (CHRU)

Status: Completed

Conditions: Preoperative Fasting and Hypotension

Study type: Observational

Funder types: Other

Identifiers

NCT02891122

JEÛNE PREOPERATOIRE

Details and patient eligibility

About

This study aims to determine if prolonged fasting represents an independent risk factor for hypotension during induction of general anesthesia in the elderly.

Full description

Preoperative fasting aims to reduce the risk of adverse events (eg, inhalation), but may be responsible for dehydration whose consequence is a major hypotension. This problem of hypotension is important because it (MAP <55 mmHg) is directly correlated to the occurrence of pejorative events on the cardiac and renal level and even more so that the duration of the hypotension is long.

Enrollment: 56 patients

Sex: All

Ages: 70+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Risk Score anesthetic ASA I-III

• Patients ≥ 70 years

• Suffering from a femoral neck fracture to be treated surgically:

  • either through prosthesis,
  • either by intramedullary nailing (gamma nail)

Exclusion criteria

• Risk Score anesthetic ASA IV
• Patient on Angiotensin Converting Enzyme (ACE) inhibitors or ARBs (ARA2) within 10 hours before surgery
• Obesity (BMI> 35) or weight <40kg
• Need to make a rapid sequence induction
• Inability to achieve the femoral block (standardization of induction) or patient refusal with respect to the technique.