Effect of the Extract of the Flour Fermented With Bacillus Subtilis Var Natto DC-15 on Postprandial Glucose

Hiroshima University

Status: Completed

Conditions: Prediabetes

Treatments: Dietary Supplement: Placebo; Dietary Supplement: Bacillus subtilis var natto DC-15

Study type: Interventional

Funder types: Other

Identifiers

NCT02300181

eki-1051

Details and patient eligibility

About

The purpose of the present study is to evaluate the effect of the extract of the flour fermented with Bacillus subtilis var natto DC-15 on postprandial glucose level in subjects with prediabetes.

Enrollment: 20 patients

Sex: All

Ages: 35 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Fasting plasma glucose 110-125 mg/dL

Exclusion criteria

• Taking anti-diabetic drugs
• Taking drugs or functional food that may affect blood glucose level
• Pregnant or nursing a child
• Participation in any clinical trial within 90 days of the commencement of the trial
• Renal or hepatic dysfunction
• Heart disease
• History of severe disease and/or major surgery

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Triple Blind

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20 participants in 2 patient groups, including a placebo group

Placebo (flour)

Placebo Comparator group

Description:

5 placebo capsules for each test (4.88 kcal/5 cap)

Treatment:

Dietary Supplement: Placebo

Bacillus subtilis var natto DC-15

Experimental group

Description:

5 experimental capsules for each test (4.96 kcal/5 cap) Extract powder of the flour fermented with Bacillus subtilis var natto DC-15

Treatment:

Dietary Supplement: Bacillus subtilis var natto DC-15