Effect Of The Mediterranean Diet On Zonulin And Infertility

SINEM BAYRAM

Status: Completed

Conditions: Intestinal Permeability; Infertility Female; Mediterranean Diet; Zonulin

Treatments: Behavioral: mediterranean diet

Study type: Interventional

Funder types: Other

Identifiers

NCT07072936

SINEM BAYRAM

Details and patient eligibility

About

The goal of this clinical trial is to learn if mediterranean diet works to treat infertility in women. It will also learn about the initial and end of study zonulin levels of mediterranean diet and control group. The main questions it aims to answer are:

• Does mediterranean diet lower the serum zonulin levels of participants?
• Does mediterranean diet improves the treatment success of participants with infertility? Researchers will compare mediterranean to a control group to see if diet works to treat infertility.

Participants will:

• Apply Mediterranean diet or routine diet without energy restriction for 8 weeks
• Visit the clinic once every 4 weeks for checkups and tests

Enrollment: 22 patients

Sex: Female

Ages: 20 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Being in the range of 18.5-29.9 kg/m2 BMI
• Having started infertility treatment

Exclusion criteria

• Having a chronic disease (diabetes mellitus, hypertension, etc.)
• Previous ovarian surgery
• Being diagnosed with PCOS, endometriosis
• Known autoimmune disease
• Thyroid disease

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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22 participants in 2 patient groups

mediterranean diet group

Experimental group

Description:

this group will apply mediterranean diet for 8 weeks

Treatment:

Behavioral: mediterranean diet

control group

No Intervention group

Description:

this group will apply routine diet for 8 weeks