Effect of the Omentectomy on the Hyperglycemia and the Resistance to the Insulin in Patients With Morbid Obesity (omentectomy)

Universidad de Guanajuato

Status and phase

Completed

Early Phase 1

Conditions

Diabetes Mellitus Type 2

Obesity

Treatments

Procedure: omentectomy

Study type

Interventional

Funder types

Other

Identifiers

NCT00454597

0910-0459

ID :0910-0459

Details and patient eligibility

About

To determine if the omentectomy diminishes hyperglycemia and improves the resistance to the insulin in patients with morbid obesity and propensity to develop to Diabetes Mellitus type 2.

Full description

To determine the Blood levels of glucose, curve of tolerance to the glucose, hemoglobin glycosylated, insulin, triglyceride, cholesterol, HDL, LDL, leptin and Adiponectin in patients with Obesity Morbid and that will be put under umbilical surgery and cholecystectomy opened.

To put under them umbilical surgery or Cholecystectomy open with and without omentectomy To compare the Blood levels of of glucose, curve of tolerance wing glucose, hemoglobin glycosylated, insulin, triglyceride, cholesterol, HDL, LDL, leptin and Adiponectin before and after the procedure

Enrollment

21 patients

Sex

All

Ages

18 to 90 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

All the patients with Obesity Morbid who suffer of hernia umbilical Chronic Cholecystitis Lithiasic non worsened.
Patient with age between the 18 to 55 years of age.
Both sorts.
Patient with index of corporal mass from 30 to 35.
Patient with index waist greater or equal hip of 100cm in men and women greater of 88cm.
Patient that has a central glucose of 100 to 125mg.
Patient that has a tolerance to the glucose of 140 to 200mg.
Patient which they have a result of triglyceride in blood of 300 or greater.
Patient that has values of LHD below 40 mg/dl.

Exclusion criteria

Patient that they have I diagnose already established of Diabetes Mellitus type 2 and in medical treatment.
Patient with elevation of hepátic enzymes (more than 50% of the superior limits of normality) and/or creatinin in 1,5 serum > mg/Dl.
Patient with Diabetic ketoacidosis history.
Uso of oral anticoagulants.
Positive Test of pregnancy (Human Chorionic Gonadotropin ) for women.
Recurrent Infections and at the time of the study.
Umbilical Hernia complicated and strangled or Worsened Chronic Cholecystitis.