Effect of the Sheath of Rectus Abdominis Block Combined With the Transverse Plane

Tongji Hospital

Status

Unknown

Conditions

Nerve Block

Surgical Conditions

Treatments

Procedure: abdominal nerve block

Study type

Interventional

Funder types

Other

Identifiers

NCT04850404

1900026767

Details and patient eligibility

About

The situation of demand for surgical conditions is quite high when lymph node resection involved in the surgery type, especially abdominal aortic lymph node dissection, and commonly, the surgeons complained about the interference from the intestine which pushed the investigators to increase the level of neuromuscular blockade close to deep NMB. To avoid the application of deep NMB and promote good surgical conditions for laparoscopic gynecological surgery with lymph nodes resection, the investigators explored other preoperative ways to cooperate with surgeons more harmoniously. It's well known that epidural anesthesia and epidural anesthesia combined with spinal anesthesia have the effect of muscle relaxation which has been applied in clinical practice widely. One study indicated that the Transverse Abdominal Plane (TAP) block could change muscle thickness and achieve the effect of muscle relaxation. It leads investigators to a hypothesis that the sheath of rectus abdominis block combined with transverse abdominal plane block may suppress the signal transmission of abdominal nerve, and may be beneficial to improve surgical conditions.

Full description

The investigators conducted this study to test the hypothesis that compared with moderate NMB， the sheath of rectus abdominis block combined with transverse abdominal plane block may reduce the frequency of additional ask for muscle relaxants to optimize surgical conditions, and also provide postoperative analgesia on the premise of moderate NMB.

Enrollment

42 estimated patients

Sex

Female

Ages

18 to 55 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

ASA grade I~ II;
aged 18-55 years;
BMI 19 ~ 23kg/m2;
laparoscopic total hysterectomy and bilateral adnexectomy and/or pelvic lymphadenectomy under elective general anesthesia lasted for more than 2 hours; 5. informed consent has been signed.

Exclusion criteria

the patient had a history of abdominal surgery;
For patients who are professional athletes and weight trainers, abdominal muscle tension can be changed through strength training need to be excluded.
allergic to any of the drugs used in the experiment;
pregnant or lactating women;
patients with severe mental and neurological symptoms cannot cooperate with the study;
those who participated in other clinical trials within 3 months before being enrolled in the study;
the researcher believes that other reasons are not suitable for clinical trials;
patients who have changed their surgical methods or received only palliative surgical treatment;
patients with abnormal coagulation function;