Effect of Thrombus Aspiration in Patients With Myocardial Infarction Presenting Late After Symptom Onset

University of Leipzig

Status and phase: Completed; Phase 4

Conditions: Myocardial Infarction

Treatments: Device: manual thrombus aspiration (Export catheter, Medtronic Inc. Minneapolis, Minnesota, USA)

Study type: Interventional

Funder types: Other

Identifiers

NCT01379248

STEMI-Late-Presenter

Details and patient eligibility

About

The purpose of this study is to examine the benefit of thrombus aspiration in patients with ST-elevation myocardial infarction presenting late after symptom onset.

Enrollment: 152 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ST-elevation myocardial infarction >12 and <48 hours after symptom onset
• age 18 to 90 years
• informed consent

Exclusion criteria

• prior fibrinolysis
• severe comorbidities with limited life expectancy
• pregnancy
• patient unable to give informed consent
• participation in another trial
• contraindications for heparin, aspirin or thienopyridines
• contraindications for cardiac magnetic resonance examination

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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152 participants in 2 patient groups

thrombus aspiration

Experimental group

Description:

Manual thrombus aspiration with dedicated catheter (Export, Medtronic Inc. Minneapolis, Minnesota, USA)

Treatment:

Device: manual thrombus aspiration (Export catheter, Medtronic Inc. Minneapolis, Minnesota, USA)

no thrombus aspiration

No Intervention group