Effect of Thyroid Hormone on Post-Myocardial Infarction Remodeling and Prognosis in STEMI Patients (ThyREST)

Capital Medical University

Status: Unknown

Conditions: Thyroid; STEMI; Cardiac Remodeling, Ventricular

Treatments: Other: Thyroid hormone levels

Study type: Observational

Funder types: Other

Identifiers

NCT03933358

BFH-Thyroid and STEMI

Details and patient eligibility

About

This study aims to determine whether thyroid hormone levels are predictive of cardiac remodeling following myocardial infarction and the prognosis in patients with STEMI receiving primary percutaneous coronary intervention.

Enrollment: 250 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• with a confirmed STEMI diagnosis
• undergoing primary percutaneous coronary intervention (presenting <12h after symptom onset)
• patients agreed and provided informed consent

Exclusion criteria

• past history of myocardial infarction or percutaneous coronary intervention or coronary artery bypass graft
• past history of heart failure (LVEF<40%) or myocardiopathy or atrial fibrillation
• past history of thyroid diseases, or were treated with amiodarone, dopamine, or corticosteroids before hospital admission
• contraindicating to cardiac magnetic resonance imaging

Trial design

250 participants in 2 patient groups

Euthyroid

Treatment:

Other: Thyroid hormone levels

Low T3

Description:

low triiodothyronine syndrome

Treatment:

Other: Thyroid hormone levels