Effect of Timing of a Post-exercise Oral Glucose Tolerance Test on Glycaemic Control.

Northumbria University

Status: Suspended

Conditions: Area Under Curve [N06.850.520.830.200]

Treatments: Behavioral: Rest; Behavioral: Delay; Behavioral: Exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT01987687

32W7

Details and patient eligibility

About

Postprandial glycaemic control is an important risk factor for the development of type 2 diabetes, cardiovascular disease and all-cause mortality.

Previous research has demonstrated that exercise performed in the postprandial state paradoxically results in a deterioration in glucose tolerance in the immediate post-exercise period (Gonzalez et a. 2013; Gonzalez and Stevenson 2013). This study aims to assess the timecourse of this post-exercise effect.

Enrollment: 12 estimated patients

Sex: Male

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Normal weight (18-25 kg/m2)
• Physically active (>or= 3 times per week)
• Male

Exclusion criteria

• Contraindications to exercise
• Food intolerances
• Food allergies

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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12 participants in 3 patient groups

Rest

Active Comparator group

Description:

Breakfast followed by a rest period prior to OGTT.

Treatment:

Behavioral: Rest

Exercise-immediate

Experimental group

Description:

Breakfast followed by exercise and an immediate OGTT

Treatment:

Behavioral: Exercise

Exercise-delay

Experimental group

Description:

Breakfast followed by exercise and a delayed (1 h) OGTT.

Treatment:

Behavioral: Exercise

Behavioral: Delay