Effect of Topical Dexmedetomidine on Intraocular Pressure

Beirut Eye Specialist Hospital

Status and phase: Completed; Phase 4

Conditions: Glaucoma; Intraocular Pressure

Treatments: Drug: Balanced salt solution; Drug: Dexmedetomidine

Study type: Interventional

Funder types: Other

Identifiers

NCT03690622

BeirutEyeSH

Details and patient eligibility

About

Evaluate the short-term safety and efficacy of dexmedetomidine (0.0055%) drops on intraocular pressure (IOP) in healthy eyes.

Enrollment: 49 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients with healthy eyes and no history of glaucoma

Exclusion criteria

• history of glaucoma, IOP > 24mmHg at baseline, abnormal optic nerve on fundus examination, keratoconus, corneal graft, corneal edema or a history of refractive surgery

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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49 participants in 2 patient groups

BSS

Sham Comparator group

Description:

Balanced salt solution

Treatment:

Drug: Balanced salt solution

Dexmedetomidine

Active Comparator group

Description:

dexmedetomidine (0.0055%)

Treatment:

Drug: Dexmedetomidine