Effect of Total Intravenous Anesthesia and Balanced Anesthesia on Postoperative Lung Function

Medical University Innsbruck

Status and phase: Completed; Phase 4

Conditions: Lung Function

Treatments: Drug: remifentanil; Drug: Sevoflurane/Nitrous Oxide; Drug: propofol; Drug: fentanyl

Study type: Interventional

Funder types: Other

Identifiers

NCT00706277

2007-007161-25

Details and patient eligibility

About

The aim of the study is to investigate the effects of total intravenous anesthesia (TIVA; propofol, remifentanil) and balanced anesthesia (BAL; induction with propofol and fentanyl; maintenance of anesthesia with sevoflurane and nitrous oxide) on pulmonary function 30 minutes after emergence from the general anesthesia.

Enrollment: 60 estimated patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA 1-2
• BMI normal

Exclusion criteria

• lung disease
• Nicotine abuse

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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60 participants in 2 patient groups

TIVA

Active Comparator group

Description:

patients receiving total intravenous anesthesia (TIVA)

Treatment:

Drug: propofol

Drug: remifentanil

balanced

Active Comparator group

Description:

patients receiving balanced anesthesia

Treatment:

Drug: fentanyl

Drug: propofol

Drug: Sevoflurane/Nitrous Oxide