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Effect of Triple Pre-rehabilitation on Radiotherapy for Head and Neck Cancer Patients

P

Peking University

Status

Completed

Conditions

Radiotherapy
Head and Neck Cancer
Triple Pre-rehabilitation

Treatments

Other: triple rehabilitation
Other: triple pre-rehabilitation

Study type

Interventional

Funder types

Other

Identifiers

NCT05594069
Pre-rehabilitation

Details and patient eligibility

About

To evaluate the intervention effect of triple pre-rehabilitation on head and neck cancer patients with radiotherapy, and process evaluation to further optimize the intervention program.

The pre-rehabilitation intervention was develped previously based on the process of evidence-based-nursing, including interventions of nurtrtion, exercise, and psychology.

Enrollment

87 patients

Sex

All

Ages

18 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • 18≤ age < 75 years old
  • The pathological diagnosis of HNC included nasopharyngeal cancer, oral cancer, oropharyngeal cancer, hypopharyngeal cancer, laryngeal cancer, salivary gland cancer;
  • Plan to receive radiotherapy
  • Basic communication skills
  • Volunteer to participate in this study.

Exclusion criteria

  • Combined with other malignant tumors
  • Distant metastasis
  • Inability to measure body composition, such as metal in the body or inability to stand alone
  • With contraindications to exercise (such as cardiovascular and cerebrovascular diseases, respiratory diseases, etc)
  • Complicated with severe liver and kidney function damage
  • Previous diagnosis of other cancers
  • pregnant or lactation women.

Trial design

Primary purpose

Supportive Care

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

87 participants in 2 patient groups

Pre Group
Experimental group
Description:
intervention before and during radiotherapy
Treatment:
Other: triple rehabilitation
Other: triple pre-rehabilitation
Re Group
Other group
Description:
intervention during radiotherapy only
Treatment:
Other: triple rehabilitation

Trial documents
1

Trial contacts and locations

1

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Central trial contact

Lichuan Zhang, PhD student

Data sourced from clinicaltrials.gov

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