Effect of Turmeric on Diabetic Nephropathy

Shaheed Faghihi Hospital

Status: Completed

Conditions: Diabetic Nephropathy; Proteinuria

Treatments: Drug: Angiotensin-converting enzyme (ACE) inhibitor + Angiotensin-II type 1 receptor (ATI) blocker; Drug: Turmeric extract

Study type: Interventional

Funder types: Other

Identifiers

NCT01015937

3997

Details and patient eligibility

About

The purpose of this study is to investigate whether turmeric is effective in improvement of diabetic nephropathy and in decrease in the amount of proteinuria and cytokine levels.

Full description

Diabetic nephropathy is leading cause of ESRF that many therapy recommended for it. In this study, we investigate effect of turmeric on diabetic nephropathy, thus we selected diabetic nephropathy patients and divided them into 2 groups. One group received turmeric + ACE inhibitor + Angiotensin II receptor blocker (ARB) and the second group received only ACE inhibitor + ARB.

Enrollment: 50 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• diabetic nephropathy
• more than 300 mg proteinuria/day
• age more than 18 years old

Exclusion criteria

• DM type 1

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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50 participants in 2 patient groups

Turmeric

Active Comparator group

Description:

diabetic nephropathy patient more than 300 mg/proteinuria

Treatment:

Drug: Turmeric extract

ACE inhibitor + ATI blocker

Active Comparator group

Description:

diabetic nephropathy more than 300 mg/day proteinuria

Treatment:

Drug: Turmeric extract

Drug: Angiotensin-converting enzyme (ACE) inhibitor + Angiotensin-II type 1 receptor (ATI) blocker