Effect of Turmeric on Pruritus in Hemodialysis Patients

Shiraz University of Medical Sciences

Status and phase: Completed; Early Phase 1

Conditions: End Stage Renal Failure

Treatments: Drug: turmeric; Drug: placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT01037595

3441

Details and patient eligibility

About

The purpose of this study is to see whether turmeric can be effective in treatment of pruritus in hemodialysis patients.

Full description

pruritus is a common in hemodialysis patients and many treatment recommended for it . as turmeric has anti-inflammatory , anti-cytokine and anti-oxidant effect it may effective in treatment of uremic pruritus. thus we compared turmeric with placebo in this study

Enrollment: 60 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Hemodialysis for more than 3 months
• More than 18 years old
• Pruritus

Exclusion criteria

• Use other treatment for pruritus

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 2 patient groups, including a placebo group

turmeric

Experimental group

Description:

turmeric 500 mg tid orally for 8 weeks

Treatment:

Drug: turmeric

Drug: turmeric

plasebo

Placebo Comparator group

Description:

placebo tid orally for 8 weeks

Treatment:

Drug: placebo