Effect of Ultrasound-guided Stellate Ganglion Block Combined With Facial Nerve and Glossopharyngeal Nerve Block on the Treatment of Sudden Deafness

Zhuan Zhang

Status: Enrolling

Conditions: Sudden Deafness

Treatments: Procedure: Facial and glossopharyngeal nerve blocks; Procedure: Stellate ganglion block; Drug: Mecobalamin Tablets

Study type: Interventional

Funder types: Other

Identifiers

NCT05623384

20221031

Details and patient eligibility

About

Sudden deafness is a sudden, unexplained sensorineural hearing loss of ≥20 dBHL in at least two adjacent frequencies within 72 h. It may be accompanied by tinnitus, a sense of ear congestion, vertigo and other Symptoms.Stellate ganglion block increases the blood flow and blood velocity in the inner ear, keeping the body's vegetative, endocrine and immune functions normal.The branches of the facial and linguopharyngeal nerves are connected to the inner ear, and local injection can nourish the nerves and improve local circulation.

Enrollment: 90 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Meet the diagnostic criteria for sudden deafness established by the Editorial Board of the Chinese Journal of Otolaryngology, Head and Neck Surgery and the Chinese Society of Otolaryngology, Head and Neck Surgery
• Age 18 to 80 years
• ASA classification Ⅰ~Ⅲ grade

Exclusion criteria

• Acoustic conductance test, vestibular function test, cranial MRI, etc. suggest organic disease
• People with coagulation disorders or on anticoagulation therapy
• Infection at the puncture site
• Severe systemic diseases that cannot cooperate with treatment

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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90 participants in 3 patient groups

Stellate ganglion block combined with facial and glossopharyngeal nerve block group

Experimental group

Treatment:

Procedure: Facial and glossopharyngeal nerve blocks

Procedure: Stellate ganglion block

Drug: Mecobalamin Tablets

Stellate ganglion block group

Experimental group

Treatment:

Procedure: Stellate ganglion block

Drug: Mecobalamin Tablets

Control group

Other group

Treatment:

Drug: Mecobalamin Tablets