Effect of Ureteral Stents Length and Location on Related Symptom

Taipei Medical University

Status: Completed

Conditions: Lower Urinary Tract Symptoms; Overactive Bladder Syndrome

Treatments: Device: Ureteral Stent of 5-22 or 5-24; Device: Ureteral Stent of 5-16 or 5-18

Study type: Interventional

Funder types: Other

Identifiers

NCT05069376

N201802031

Details and patient eligibility

About

This is a prospective randomized clinical trial, evaluating the effect of the intra-ureteral placement of the stent's distal end versus the conventional stent placement on the postoperative LUTS and pain.

Full description

Intravesical stent mass has been considered to cause stent-related symptoms, such as LUTS and pain. The current study hypothesized that the total intra-ureteral placement of the stent's distal end could decrease postoperative LUTS and pain. We proposed a prospective randomized trials, investigating the effect of intra-ureteral stent placement versus conventional stent placement. The primary end point was postoperative LUTS. The secondary end points were postoperative pain and quality of life. We used USSQ questionnaire as the assessing tool.

Enrollment: 103 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of unilateral ureteral stone
• Plan to undergo unilateral URS lithotripsy
• Adult patients (>18 years old)

Exclusion criteria

• Pre-stented cases
• Distal ureteral stones
• Preoperative urinary tract infection
• With medications known to influence stent-related symptoms, including alpha-blockers, antimuscarinics, beta3-agonist
• Pregnancy
• Other procedures required during the procedure of lithotripsy
• A stent was expected to be indwelled for more than 10 days (ureteral stricture, ureteral tumors/polyps, ureteral trauma, and a large amount of stone fragments)

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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103 participants in 2 patient groups

The intraureteral placement of distal end of ureteral stent

Experimental group

Description:

Patients randomized to this group received 5-16/5-18 D-J stent with intraureteral placement of the distal end

Treatment:

Device: Ureteral Stent of 5-16 or 5-18

The conventional placement of the distal end of ureteral stent

Active Comparator group

Description:

Patients randomized to this group received 5-22/5-24 D-J stent with bladder placement of the distal end

Treatment:

Device: Ureteral Stent of 5-22 or 5-24