Effect of Using Different Varnishes on Dentin Hypersensitivity; Na Fluoride and Nano-silver Fluoride

Nayera Hassanien Mohamed

Status: Unknown

Conditions: Dentin Hypersensitivity

Treatments: Behavioral: Citrine 5 % sodium fluoride; Behavioral: concocted nano-silver fluoride

Study type: Interventional

Funder types: Other

Identifiers

NCT04731766

205

Details and patient eligibility

About

2 different varnishes will be used to test their effectiveness in controlling teeth hypersensitivity in adult patient.

Full description

In-vivo part:

Each varnish will be applied separately on different teeth according to the manufacturer's instructions and the VAS will be measured according to a specific timeline: T0 (baseline, before application of varnish), T1 (1 week after application), T2 (4 weeks after application) and T3 (4 weeks after application).

In-situ part:

Dentin specimen will be prepared from extracted teeth from the orthodontic department in our college, sterilized and prepared.

it will be bonded to an orthodontic wire and bonded to upper first molar. Dentinal occlusion will be measured using scanning electron microscope following the same timeline.

Enrollment: 42 estimated patients

Sex: All

Ages: 25 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients consulting in one of the Qasr Einy, faculty of dentistry outpatient clinics.
• Males or females.
• Patient's age range 25-50 years.
• Patients complaining of hypersensitive areas on facial surfaces of the teeth (incisors, cuspids, bi-cuspids, and first molars with exposed cervical dentine) with teeth scoring Bpain (VAS score: greater than or equal to 3) during application of stimulus (airblast and tactile sensitivity test).
• Tooth with exposed root surface, complaining from hypersensitivity (VAS score; greater than or equal to 3).
• Patients accept the 2-months follow-up period.
• Provide informed consent.

Exclusion criteria

• • Patients participating in another dental study that may alter the results of this study.

  • A medical condition that could hinder the accuracy of pain reporting (e.g., pain disorders).
  • Any chronic medical condition that requires the regular use of anti-inflammatory pain medications.
  • Patients used or applied a desensitizing varnish within the last four weeks.
  • Patients with dental problems; chipped teeth, defective restorations, fractured Un-displaced cuspids or deep dental caries.
  • Lack of patient's approval and compliance.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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42 participants in 2 patient groups

Citrine 5% Sodium Fluoride

Active Comparator group

Description:

It was developed to prolong the contact between the tooth surface and fluoride to increase the resistance against caries attack and manage tooth hypersensitivity; the active ingredient of fluoride varnish is mostly 5% sodium fluoride.

Treatment:

Behavioral: Citrine 5 % sodium fluoride

concocuted Nano-silver fluoride

Experimental group

Description:

Nano-silver fluoride (NSF) is a laboratory synthesized solution

Treatment:

Behavioral: concocted nano-silver fluoride