Effect of Using Whey Protein and Creatine Supplements on Muscular Strength in Weight-training Adult Males

GlaxoSmithKline (GSK)

Status and phase: Completed; Phase 1

Conditions: Nutritional Status

Treatments: Dietary Supplement: Placebo; Dietary Supplement: Whey protein only supplement; Dietary Supplement: Whey protein and creatine supplement

Study type: Interventional

Funder types: Industry

Identifiers

NCT02094781

200616

RH01717 (Other Identifier)

Details and patient eligibility

About

The purpose of this study was to evaluate the effect of combined whey protein and creatine supplement, as compared with whey protein supplement alone, on change in upper and lower body strength.

Enrollment: 18 patients

Sex: Male

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Recreationally active males
• Age 18 to 35 years
• BMI 19 to 29.9 kg/m2
• Weight training 3 to 4 times a week for at least 6 months before the trial

Exclusion criteria

• Participants with medical conditions including active heart disease, high blood pressure, renal or hepatic impairment type I or II diabetes, bipolar disease, pulmonary disease, thyroid disease, immune disorder, psychiatric disorder
• Dietary or herbal supplement used in the past 60 days to increase muscle mass
• Use of protein supplement in the past 7 days
• Use of thermogenic supplement or beverage in the past 7 days
• Use of Non-steroidal anti inflammatory drugs or corticosteroids in the past 7 days

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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18 participants in 3 patient groups, including a placebo group

Whey protein and creatine supplement

Experimental group

Description:

Each sachet contained 30g whey protein powder and 5g creatine powder, administered twice a day. The first serving was consumed with breakfast and the second serving was consumed within 60 minutes of completing training or in the evening on non-training days. Participants also drank at least 2 litres of water per day

Treatment:

Dietary Supplement: Whey protein and creatine supplement

Whey protein only supplement

Active Comparator group

Description:

Each sachet contained 30g of whey protein powder and 5g of bulking agent powder, administered twice a day. The first serving was consumed with breakfast and the second serving was consumed within 60 minutes of completing training or in the evening on non-training days. Participants also drank at least 2 litres of water per day

Treatment:

Dietary Supplement: Whey protein only supplement

Placebo

Placebo Comparator group

Description:

Each sachet contained 30g of isocaloric carbohydrate powder and 5g of bulking agent powder, administered twice a day. The first serving was consumed with breakfast and the second serving was consumed within 60 minutes of completing training or in the evening on non-training days. Participants also drank at least 2 litres of water per day

Treatment:

Dietary Supplement: Placebo