Effect of Vagus Nerve Stimulation on Chronic Stroke Patients

Medipol Health Group

Status: Enrolling

Conditions: Stroke

Treatments: Device: Non-invasive auricular vagus nerve stimulation; Other: Conventional therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT05779293

Stroke

Details and patient eligibility

About

Stroke is still one of the top causes of death and adult-onset disability in the world.

Despite physiotherapy and rehabilitation, a sizable percentage of chronic stroke patients are permanently disabled. These neurological deficiencies include cognitive impairment, sensory impairment, loss of coordination, spasticity, dysphasia, dysphagia, visual field dysfunction, and weakness.

Full description

Exercises, neurophysiological and electrical stimulations, compensatory strategies, strengthening facilitation approaches programs, and programs are all used as general approach methods in the rehabilitation of stroke patients.

Transcutaneous stimulation of the vagus nerve offers non-invasive stimulation of the vagus nerve and is commonly carried out by stimulating the auricular vagus nerve in the ear or transcutaneous cervical branch vagus in the neck.

Enrollment: 40 estimated patients

Sex: All

Ages: 40 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• To be between the ages of 18-80.
• Having been diagnosed with a stroke by a neurologist.
• Speech disorder after a cerebrovascular accident to be.
• To volunteer to participate in the study.

Exclusion criteria

• Being mentally affected (Mini-Mental Test Score <24).
• Having other neurological diseases other than stroke.
• Concomitant symptoms that prevent individuals from participating in the study (Having undergone amputation surgery, having cardiac arrhythmias be etc.)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 2 patient groups

non-invasive auricular vagus nerve stimulation

Experimental group

Description:

non-invasive auricular vagus nerve stimulation + Neuromuscular Electrical Stimulation (NMES) exercise under the supervision of a physiotherapist

Treatment:

Device: Non-invasive auricular vagus nerve stimulation

Conventional physical therapy

Active Comparator group

Description:

NMES exercise under the supervision of a physiotherapist

Treatment:

Other: Conventional therapy