Effect of Valsartan on Left Ventricular Myocardial Functions in Hypertensive Patients With Left Ventricular Hypertrophy

Mustafa Kemal University

Status and phase: Completed; Phase 4

Conditions: Hypertension; Left Ventricular Hypertrophy

Treatments: Drug: valsartan

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT01425411

vals262626

Details and patient eligibility

About

The study hypothesis: Valsartan as an angiotensin II receptor blocker treatment has beneficial effects on both midwall mechanics and myocardial functions in hypertensive patients with Left ventricular hypertrophy.

Enrollment: 38 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• hypertension with left ventricular hypertrophy

Exclusion criteria

• clinical or laboratory evidence of secondary hypertension
• heart failure
• ischemic heart disease
• valvular heart disease
• arrhythmias
• peripheral vascular disease
• chronic obstructive pulmonary disease
• neurologic disorders
• diabetes mellitus
• renal dysfunction
• notable systemic disease

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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38 participants in 1 patient group

Valsartan treatment

Experimental group

Treatment:

Drug: valsartan