Effect of Vitamin D3 and Omega-3FA on Leptin and HbA1C With Vitamin D Deficiency

Applied Science Private University

Status: Completed

Conditions: Vitamin D Deficiency

Treatments: Dietary Supplement: VD3 and omega- 3FA group; Dietary Supplement: omega 3 FA group; Dietary Supplement: VD3 group; Other: control group

Study type: Interventional

Funder types: Other

Identifiers

NCT03735303

DRGS-4-2018

Details and patient eligibility

About

The Combined effect of Vitamin D3 and Omega-3 supplements on serum leptin and Glycated hemoglobin (Hb A1C) levels in Jordanian people with vitamin D deficiency.

Full description

Nothing is published in the literature about effect of vitamin D3 (VD3) and omega-3 fatty acids (omega-3FA) on serum leptin and glycated hemoglobin ( HbA1C)

This study will be conducted to investigate effect of VD3 and omega-3FA alone and with each other on serum leptin and Glycated hemoglobin (Hb A1C) levels in Jordanian people with vitamin D deficiency.

This randomized, controlled clinical trial will be designed to test effects of 50,000 IU VD3 weekly and 1000 mg omega-3FA daily for eight weeks, separately and with each other, on on serum leptin and Glycated hemoglobin (Hb A1C) levels .

Enrollment: 146 patients

Sex: All

Ages: 25 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• jordanian people aged 25-55
• medical diagnosis of vitamin D deficiency ( VD <25 ng/ ml)

Exclusion criteria

• Blood disorders including
• thalassemia
• sickle cell disease

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

---

146 participants in 4 patient groups

VD3 group

Experimental group

Description:

dietary supplement : VD3 group treated with 50000 IU VD3/ week for 8 weeks

Treatment:

Dietary Supplement: VD3 group

omega 3- FA group

Experimental group

Description:

dietary supplement : omega 3- FA group 1000 mg wild salmon and fish oil complex (contain 300 mg of omega 3-FA) once daily for 8 weeks

Treatment:

Dietary Supplement: omega 3 FA group

VD3 and omega 3 FA group

Experimental group

Description:

dietary supplement : VD3 and omega-3FA 50000 IU VD3/week for 8 weeks and 1000 mg wild salmon and fish oil complex (contain 300 mg of omega 3-FA) once daily for 8 weeks

Treatment:

Dietary Supplement: VD3 and omega- 3FA group

control group

Experimental group

Description:

no intervention was given

Treatment:

Other: control group