Effect of WB-EMS on Parkinson's Disease

Università degli studi di Roma Foro Italico

Status: Invitation-only

Conditions: Parkinson Disease

Treatments: Other: Control group; Other: Cardiovascular training with WB-EMS; Other: Strenght training combined with WB-EMS

Study type: Interventional

Funder types: Other

Identifiers

NCT04878679

ForoItalico1

Details and patient eligibility

About

The aim is to establish adequate and suitable protocols for PD patients and to determine the WB-EMS effects on muscle strength, balance, walking, cognitive functions,neurotrophic factors and alpha-synuclein. Thirty-six PD patients, aged from 50 to 80 years, will be recruited and randomly assigned to two experimental groups (EGs and EGc) and one control group (CG), in order to perform dynamic movements with WB-EMS. EGs will undergo to 12-20 minutes of progressive supervised WB-EMS (4 sec. 85 HZ and 4 sec. rests) combined to light dynamic movements, two-time per week for 12/24 weeks. EGe will undergo to 12-20 minutes of progressive supervised WB-EMS 7 Hz) combined with cardiovascular training with rowing machine. CG will not perform any type of physical activity. Pre and post intervention assessment will be carried out on the following areas: physical assessment, neurocognitive, neurotrophic factors and alpha-synuclein assesments. A 3 months follow-up will be performed.

Enrollment: 36 estimated patients

Sex: All

Ages: 50 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• age from 50 to 80 years old
• clinical diagnosis of parkinson's disease from 1 to 3 of Hoehn and Yahr Scale
• no partecipation to other physical activity program

Exclusion criteria

• MMSE values < 24
• inability to walk 6 minutes without assistance
• use of medications and other things that may affect cognitive and motor functions
• presence of contraindications in the use of WB-EMS

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: None (Open label)

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36 participants in 3 patient groups

"Strength training + WB-EMS"

Experimental group

Description:

Strength training combined with WB-EMS : 2 times/week for 20 minutes

Treatment:

Other: Strenght training combined with WB-EMS

Cardiovascular training + WB-EMS

Experimental group

Description:

Cardiovascular training, using rowing machine, combined with WB-EMS : 2 times/week for 20 minutes

Treatment:

Other: Cardiovascular training with WB-EMS

Control group

Active Comparator group

Description:

No physical activity

Treatment:

Other: Control group