Effect of Weight Reduction on Inflammatory Markers and Genes Expression in Obese Individuals

Taichung Veterans General Hospital

Status: Completed

Conditions: Inflammation; Obesity

Treatments: Behavioral: Lifestyle modification

Study type: Interventional

Funder types: Other

Identifiers

NCT00416156

TCVGH 05082

Details and patient eligibility

About

To investigate whether weight reduction by life style modification for 12 weeks will improve circulating inflammatory markers, adipocytokines as well as gene expression of proinflammatory protein obtained from circulating monocytes from obese individuals.

Sex: All

Ages: 20 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Nondiabetes obese individuals with BMI greater than 27 kgs/m2

Exclusion criteria

• Diabetes
• Abnormal hepatic, renal and cardiac function