Effect Of Whole Body Vibration Versus Weight Bearing Exercises On Osteoporosis In Breast Cancer Patients After Chemotherapy

Cairo University (CU)

Status: Completed

Conditions: Osteoporosis; Breast Cancer

Treatments: Drug: vitamin D supplements and calcium; Other: Weight bearing exercises; Other: Whole body vibration group

Study type: Interventional

Funder types: Other

Identifiers

NCT05970250

Eman Mahrous Abdel-Hamed Ahmed

Details and patient eligibility

About

Chemotherapy can damage bone marrow and therefore impair the production of white blood cells, platelets and red blood cells with the resulting anemia and osteoporosis.

Full description

Purposes of this study were:

1. To determine the therapeutic efficacy of the whole-body vibration (WBV) in improving osteoporosis in breast cancer patients after receiving chemotherapy within 3-6 months.
2. To determine the therapeutic efficacy of the weight bearing exercise in improving osteoporosis in breast cancer patients after receiving chemotherapy within 3-6 months.
3. To gain knowledge about the whole-body vibration (WBV) and the weight bearing exercise in improving osteoporosis in breast cancer patients after receiving chemotherapy within 3-6 months.
4. To share in designing an ideal protocol for the treatment of the osteoporosis in breast cancer patients after receiving chemotherapy within 3-6 months.

Enrollment: 45 patients

Sex: All

Ages: 35 to 55 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Breast cancer patients after receiving chemotherapy within 3-6 months and complaining from osteoporosis.
• Their age ranges from 35-55 years old.
• All patients will have the same medical and nursing care.
• All the patients will receive a good explanation of treatment and measurement device.
• They are neurologically free.

Exclusion criteria

Patients will be excluded from this study for any of the following causes:

• Uncooperative patients.
• Instability of patient's medical condition.
• Association of another medical problem.
• Patients who have diabetes.
• Patients who have history of medical chronic relevant diseases.
• Patients who have acute or chronic hepatitis.
• Patients who have pacemaker.
• Patients who have genitourinary infections.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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45 participants in 3 patient groups

Whole body vibration group

Experimental group

Description:

In this group (the first study group) fifteen breast cancer patients after receiving chemotherapy within 3-6 months and complaining from osteoporosis were received the whole body vibration, 20 minutes 3 times per week for 2 months and drug therapy (vitamin D supplements and calcium).

Treatment:

Drug: vitamin D supplements and calcium

Other: Whole body vibration group

Weight bearing exercises group

Experimental group

Description:

In this group (the second study group) fifteen breast cancer patients after receiving chemotherapy within 3-6 months and complaining from osteoporosis were received aerobic exercise on treadmill as form of weight bearing exercise 20 minutes 3 times per week for 2 months and drug therapy (vitamin D supplements and calcium).

Treatment:

Drug: vitamin D supplements and calcium

Other: Weight bearing exercises

drug therapy group

Other group

Description:

In this group (control group) fifteen breast cancer patients after receiving chemotherapy within 3-6 months and complaining from osteoporosis were received only drug therapy (vitamin D supplements and calcium. Measurements were conducted before starting the treatment as a first record, at end of the second month of treatment as second record and make follow up after 3 months as final record.

Treatment:

Drug: vitamin D supplements and calcium