Effect of Wide Pulse Pressure on the Predictability of Stroke Volume Variation for Fluid Responsiveness in Patients Undergoing Off-pump Coronary Artery Bypass Graft

Yonsei University

Status: Completed

Conditions: Stroke Volume Variation

Treatments: Other: HES 130/0.4 (VoluvenⓇ, Fresenius Kabi, Graz, Austria) 500mL loading

Study type: Interventional

Funder types: Other

Identifiers

NCT01404455

IRB 1-2010-0039

Details and patient eligibility

About

The investigators examined the predictability of stroke volume variation for fluid responsiveness in patients with wide pulse pressure undergoing off-pump coronary artery bypass graft

Enrollment: 66 patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 1. Age ≥ 20
• 2. elective off-pump coronary artery bypass graft

Exclusion criteria

• 1. arrhythmia
• 2.EF <40%
• 3.valvular heart dz
• 4.pul HTN
• 5.PAOD
• 6.lung dz
• 7.NYHA IV
• 8.ESRD

Trial design

Primary purpose: Screening

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

66 participants in 2 patient groups

Normal pulse pressure

Other group

Description:

pulse pressure \<60mmHg

Treatment:

Other: HES 130/0.4 (VoluvenⓇ, Fresenius Kabi, Graz, Austria) 500mL loading

Wide pulse pressure

Other group

Description:

pulse pressure ≥60mmHg

Treatment:

Other: HES 130/0.4 (VoluvenⓇ, Fresenius Kabi, Graz, Austria) 500mL loading