Effect of Xen Implantation on the Aqueous Humor Proteome

Price Vision Group

Status: Terminated

Conditions: Primary Open Angle Glaucoma

Treatments: Device: Aqueous shunt; Device: Xen

Study type: Observational

Funder types: Industry

Identifiers

NCT04141865

2019-006

Details and patient eligibility

About

The purpose of this study is to determine how the aqueous humor proteome changes after implantation of a Xen microstent for treatment of glaucoma.

Full description

The purpose of this study is to determine how the aqueous humor proteome changes after implantation of a Xen microstent for treatment of glaucoma using liquid chromatography mass spectrometry.

Enrollment: 3 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Male or female of any racial or ethnic origin, 18 years or older
• Able to provide written informed consent.
• Scheduled to undergo Xen implantation for open angle glaucoma or already has an aqueous shunt

Exclusion criteria

• History of conjunctivitis or any ocular infection within the past 3 weeks.
• Any active inflammation of the cornea or the anterior chamber (uveitis)

Trial design

3 participants in 2 patient groups

Xen

Description:

Patients treated with a Xen microstent for glaucoma.

Treatment:

Device: Xen

Aqueous shunt

Description:

Patients treated with an aqueous shunt for glaucoma.

Treatment:

Device: Aqueous shunt